Blood transfusion during cardiac surgery: massive transfusion coagulopathy

Methods Total of 406 patients (f/m N=103/303) were studied in the ICU in 2011; 21 (5.17%) males were observed,. HGB in OR prior to surgery was: 127.43 g/L(SD±19.4; range 85-165; median 129g/L). Patients were divided into two groups, according to the quantity of RBCs received. Group 1 (N=15) received 5-9 units RBCs; group 2 (N=6) received ≥10 units RBCs. EuroSCORE II was used for operation risk calculation. Patients abode 6.9 days (±7.97) in ICU. LVEF was 61.1±11.06%. The consumption of RBCs, platelet concentrates (PCs), and fresh frozen plasma (FFP) within 24 h was calculated. In all these cases CBC, PT, aPTT and INR were used to evaluate perioperative bleeding. Patients were monitored prior to surgery and for the first 24 h of transfusion of blood components for creatinine, pH, Ca++, troponin I. Data are presented as median and IQR; mean and standard deviation, P < 0.05 was considered statistically significant.